In December 2025, Binance formalized her influence by promoting her to co-CEO alongside Richard Teng, who had taken over after CZ stepped down in 2023 . The move balanced Teng’s regulated-finance background with He’s deep ties to the crypto community
. She also heads YZi Labs (formerly Binance Labs), the venture capital and family-office arm that invests in Web3, AI, and biotech
. Reports from Fortune and the Wall Street Journal put her stake in Binance at roughly 10%, making her a multibillionaire and the exchange’s second-largest shareholder
.
The company didn’t keep quiet about the honor. Binance posted on X that He’s listing underscores her “vision and leadership in helping shape Binance,” and cast it as a watershed not just for her but for the wider crypto industry . The message was amplified across Binance’s global channels, framing the milestone as proof that digital-asset leaders can stand alongside executives from Citigroup, GM, and Accenture
.
Industry observers echoed the sentiment. For years, Fortune’s Most Powerful Women list included no one from the crypto sector, but He’s inclusion suggests the walls are cracking . She now sits in the same ranking as Citigroup CEO Jane Fraser (#1) and AMD chief Lisa Su (#3), a reflection of crypto’s deepening integration into mainstream finance
.
He’s influence rests on Binance’s staggering reach. As of its 2025 year-end review:
Binance also became the first global crypto exchange to win full authorization under Abu Dhabi Global Market’s framework, bridging scale and regulation . The user base grew by 90 million in just three years—from 210 million in 2022 to over 300 million by the end of 2025
. That means roughly 1 in 27 people worldwide now has a Binance account
.
Yi He isn’t slowing down. She has publicly set a target of 3 billion users, about ten times Binance’s current base . “1 billion is a clear goal, and we can achieve that,” she said earlier this year. “So for this reason, we set a more aggressive goal at the 3 billion target”
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The strategy goes beyond trading. He believes the next wave of adoption will come from payments, yield products, on-chain services, and tokenized traditional assets, not just spot or derivatives volume . In her vision, Binance transforms from a crypto exchange into “global financial infrastructure”
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That ambition tracks with broader industry trends. As of mid-2025, about 741 million people globally used crypto, and products built on crypto rails were scaling fast—real-world tokenized assets alone topped $25 billion . He’s own promotion and Fortune recognition now give her a global platform to push that narrative forward.
For a former TV host who entered the space only a decade ago, the Fortune nod is more than a personal trophy. It marks the moment crypto’s glass ceiling started to crack from the inside out.
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