DeepSeek V4 Pro: 43-Day GPU Showdown — Nvidia, AMD, Huawei, and the 110x Software Miracle

When DeepSeek dropped the 1.6-trillion-parameter V4 Pro on April 24, 2026, the real test wasn't the model's benchmark scores — it was whether any shipping hardware could serve it at million-token contexts without bankrupting the operator. SemiAnalysis fired up InferenceX and tracked every major AI accelerator for 43 straight days. The results reveal less about the chips themselves and more about the state of the software ecosystems that control them.

The Great Software Divide: Day 0 Readiness

Launch-day support split into three tiers. Nvidia's CUDA ecosystem, running on Blackwell B300 and the larger GB300 NVL72 rack-scale system, delivered full readiness immediately. vLLM and SGLang both worked out of the box, with the B300 pushing 8,075 tok/s/GPU at launch .

Huawei pulled off something genuinely historic. The Ascend 950DT + CANN framework achieved the same Day-0 full-stack support as Nvidia — the first time a non-CUDA platform has matched Nvidia on launch-day readiness for a frontier-scale model . Independent benchmarks on the shipping Ascend 950PR showed FP4 compute at 2.87x the H20's rate and MoE inference up to 1.96x faster in RL rollouts . The catch: China's hardware performance ceiling remains constrained by fabrication limits, so absolute throughput still trails Nvidia's best.

AMD's launch was, bluntly, a disaster. The MI355X could only run FP8 on Day 0 — the native FP4+FP8 checkpoint was unusable — and delivered a paltry 20.4 tok/s/GPU at 2.4 tok/s/user on the 8K/1K workload . The ROCm stack wasn't optimized; it was placeholder.

AMD's 110.5x Recovery: The Software Sprint

What followed is the most dramatic software-driven performance recovery in recent AI infrastructure memory. Over 26 days, the AMD SGLang engineering team under HaiShaw merged 31 performance optimization pull requests on the amd/deepseek_v4 side branch . Each PR addressed a layer of the ROCm stack that had been essentially untested with a MoE model of this scale.

By Day 26 (May 20, 2026), the MI355X hit 2,256 tok/s/GPU at 9.4 tok/s/user on the 8K/1K workload — a 110.5x improvement in throughput per GPU, while simultaneously improving interactivity by 3.85x . This is the rare optimization result where both axes climb together: you don't normally get faster per-user response times and higher aggregate throughput from the same hardware.

At comparable interactivity points on InferenceX, the Day-26 MI355X achieves roughly 1,411 tok/s/GPU, placing it in the same competitive tier as Nvidia's B200 at low interactivity settings . It still trails the Nvidia GB300 NVL72 (which reaches up to 11,474 tok/s/GPU under optimal conditions), but the trajectory matters: the MI355X went from a non-functional launch to a viable inference SKU .

The Full Leaderboard at 43 Days

Platform	Throughput (tok/s/GPU)	Cost ($/M tok)	Day-0 Support	Key Limitation
Nvidia GB300 NVL72	8,075–11,474	$0.064–$0.166	Full (CUDA, vLLM, SGLang)	Availability
AMD MI355X (Day 26+)	1,411–2,256	$0.291–$0.585	Broken (FP8 only, fixed later)	ROCm maturity
Nvidia B200	1,411	$0.387	Full (CUDA via Dynamo TRT)	Mid-range positioning
Huawei Ascend 950DT	No public tok/s/GPU yet	N/A	Full (CANN, Day-0)	Fabrication-constrained peak perf
Nvidia H200	186	N/A	Full (CUDA)	Previous-gen Hopper

Cost-per-million-tokens tells the economic story. At low interactivity, GB300 NVL72 delivers tokens at $0.064/M tok — roughly 4.5x cheaper than the MI355X at $0.291/M tok . At higher interactivity (lower concurrency, higher per-user speed), the MI355X becomes cost-competitive against the B200, with both hovering around $1.22–$1.45/M tok at 23–24 concurrent users .

The Real Enabler: DeepSeek V4's Hybrid Attention Architecture

The benchmark numbers are dramatic, but they'd be economically meaningless without DeepSeek's architectural breakthrough on the model side. Standard Transformer attention scales quadratically with context length. At 1 million tokens, the compute and memory costs make serving economically infeasible on any hardware. DeepSeek V4 replaces standard attention with a hybrid of two complementary mechanisms:

Compressed Sparse Attention (CSA) operates at the fine-grained level. It groups roughly 4 tokens into a single learned KV entry using data-dependent weighting with overlapping windows, then applies sparse selection — each query only attends to the top-k most relevant compressed entries, indexed by a component called the Lightning Indexer . A sliding window attention branch runs alongside to preserve local precision .

Heavily Compressed Attention (HCA) takes a coarser bet. It compresses up to 128 tokens into a single KV entry and applies dense attention over the heavily compressed stream . This trades retrieval precision for comprehensive global coverage at near-zero marginal cost. HCA runs in early layers to provide a cheap contextual panorama; the final layer retains full attention for maximum precision .

The combined efficiency gains are staggering compared to DeepSeek V3.2 at 1M tokens:

• Per-token inference FLOPs: 27% of V3.2 (73% reduction)
• KV cache memory: ~10% of V3.2 (approximately 90% reduction)
• Against a GQA bfloat16 baseline: roughly 2% of the cache footprint

For the smaller V4 Flash model, these numbers drop even further: 10% of FLOPs and 7% of KV cache .

Without CSA and HCA, the 1.6-trillion-parameter Pro model at 1M context would be a science project — interesting but commercially unservable. With them, it's a product.

What This Means

The 43-day SemiAnalysis data tells three stories in parallel. First, Nvidia's ecosystem advantage remains structurally enormous: CUDA works, Day 0, every time, and the hardware is genuinely ahead. Second, Huawei has closed the software readiness gap entirely — a historic shift with geopolitical implications that will play out over the next hardware generation. Third, AMD's hardware is capable but the ROCm software stack is still a bottleneck that requires heroic engineering effort to overcome for each new frontier model — a 110.5x improvement in 26 days is impressive, but it shouldn't be necessary.

The bigger picture belongs to the architects. DeepSeek's CSA + HCA hybrid attention doesn't just improve efficiency — it fundamentally changes what's commercially viable to serve. When a 1.6-trillion-parameter model at million-token context costs single-digit cents per million tokens on the right hardware, the conversation shifts from "can we do this?" to "what do we build with it?"