The outbreak has expanded from its epicenter in Ituri Province to a total of six provinces: Ituri, Haut-Uele, Tshopo, North Kivu, South Kivu, and most recently Bas-Uele (confirmed 13 August 2026) . Ituri remains the hardest-hit area, accounting for over 3,400 of the more than 4,660 total cases
.
The outbreak has spread to 49 health zones as of late July and has also reached neighboring Uganda (at least 2 deaths) and France (one travel-linked case) .
A critical factor driving the severity of this outbreak is the absence of any licensed vaccines or specific treatments for the Bundibugyo species . Existing Ebola vaccines, such as Ervebo, target the Zaire strain and were not designed for Bundibugyo
.
In response, the WHO is accelerating trials of experimental vaccines, therapeutics, and preventive medicines at "unprecedented speed" . On 12 August 2026, the DRC formally requested emergency doses of the Ervebo vaccine from the global stockpile for off-label use against Bundibugyo—a move driven by observational data showing that none of 242 recorded deaths with available vaccination status involved a previously vaccinated individual
.
On 14 August 2026, UN relief chief Tom Fletcher announced an additional $30.5 million from the UN's Central Emergency Response Fund (CERF) to combat the outbreak . This builds on $24 million previously allocated to the DRC and neighboring countries, plus a $60 million CERF allocation made in July 2026
. Donor countries have contributed nearly $300 million total to a dedicated fund
, and the United States announced more than $242 million in additional funding
.
The outbreak is unfolding in one of the world's most complex humanitarian environments in eastern DRC:
WHO Director-General Tedros Adhanom Ghebreyesus classified the outbreak as a Public Health Emergency of International Significance (PHEIC) . UN officials are urgently calling for a massively scaled-up international response, warning that the outbreak is "spreading faster than health authorities can contain it" and is on track to become the deadliest Ebola outbreak in history if the trajectory is not reversed . Fletcher stated bluntly: "Ebola is winning"
.