Sanofi stated it is "seeking fair compensation for use of its patented technology" and is not seeking to block sales of any vaccines .
Patents asserted: Sanofi alleges that Moderna's and Pfizer's vaccines infringe up to 10 patents held by Translate Bio covering core mRNA delivery technologies . The patents specifically relate to:
Products accused of infringement:
No fixed royalty percentage or specific dollar amount has been publicly disclosed in the complaints. Sanofi's position, per a spokesperson, is that it is seeking "fair compensation" for use of its patented technology . However, the damages at stake are enormous — the vaccines named have generated tens of billions of dollars in cumulative revenue, and Sanofi's Life Sciences IP Review notes the company is seeking damages from vaccines "worth billions" .
The lawsuits seek monetary damages (reasonable royalties) rather than injunctions, consistent with the approach other plaintiffs have taken in this patent landscape .
Sanofi's suits are the latest escalation in a dense web of high-stakes mRNA patent litigation that has been running for years. Key ongoing and recent disputes include:
| Dispute | Status |
|---|---|
| Moderna v. Pfizer/BioNTech (filed Aug. 2022) | Moderna sued Pfizer/BioNTech for infringing three patents covering the 1-methylpseudouridine mRNA modification and broad mRNA/LNP technology . Partially paused in 2024 while the USPTO reviews patent validity . The case is ongoing in the U.S. and Europe; the UK Supreme Court appeal was docketed in 2025 . |
| Genevant & Arbutus v. Pfizer/BioNTech (filed 2023) | Alleges Pfizer/BioNTech's LNP technology infringes Genevant/Arbutus patents. Still in progress . |
| Alnylam v. Pfizer & Moderna | Filed over LNP-related patents; settled after adverse decisions against Alnylam's claims . |
| Moderna's $2.25B settlement with Arbutus/Genevant (March 2026) | Moderna agreed to pay up to $2.25 billion — $950M upfront (due July 2026) plus up to $1.3B contingent on an appeal — to settle LNP patent disputes, clearing a major overhang . Notably, no future royalties are owed on Moderna's future vaccines . |
| CureVac v. Moderna (filed April 2026) | CureVac sued Moderna for infringement of mRNA technology patents . |
| BioNTech v. Moderna (filed Feb. 2026) | BioNTech countersued Moderna in a separate action . |
| Pfizer/BioNTech's challenge at the EPO | In July 2025, the European Patent Office upheld a key Moderna patent, a win for Moderna in the European theater . |
Key takeaway: Sanofi's lawsuits add a new front to what is already a multi-party, multi-jurisdictional war over foundational mRNA and LNP intellectual property. Every major mRNA vaccine player — Moderna, Pfizer/BioNTech, Sanofi/Translate Bio, CureVac, Arbutus, Genevant, Alnylam — is either suing or being sued, or both. The disputes cover three core technology pillars: mRNA sequence modifications (especially 1-methylpseudouridine), lipid nanoparticle delivery systems, and mRNA manufacturing/purification methods. Sanofi's entry specifically targets the LNP delivery and purification layer, which remains one of the most heavily contested areas in the entire landscape.