GRAM (Gradient Routed Auxiliary Modules) is an experimental pretraining method from Anthropic and AE Studio that routes dual use knowledge—like virology or cybersecurity—into dedicated modules inside an LLM, so those... In a setup with four dual use categories, a single GRAM trained model can theoretically be config...

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Anthropic and AE Studio have introduced an experimental technique called GRAM (Gradient-Routed Auxiliary Modules) that could give AI models a granular "off switch" for dangerous knowledge. Instead of training separate models for every safety configuration, GRAM aims to build a single model with removable compartments for dual-use capabilities such as virology, cybersecurity, and nuclear physics . The research is preliminary—Anthropic states it has not been applied to any production Claude model
—but it represents a promising direction for making AI safety more surgical than today's blunt toolkit.
GRAM is a pretraining method designed to localize dual-use knowledge—information that can be used for both beneficial and harmful purposes—into removable neural modules inside a language model . After training, those modules can be switched on or off, giving operators fine-grained control over which dangerous capabilities the model retains
. The same approach could also enable different access profiles for different users: researchers might turn on virology knowledge while a public-facing chatbot keeps it disabled
.
GRAM augments the standard Transformer architecture by adding small auxiliary modules—essentially dedicated neurons at every layer—that are intended to capture specific dual-use capabilities during training . The key mechanism is gradient routing: during backpropagation, weighted masks control which parameters update for which data
.
Once training is complete, individual modules can be removed or disabled to reduce access to a particular capability, or left in place for deployments that are permitted to use that knowledge . Because each dual-use category maps to its own module, a single GRAM-trained model with four categories can theoretically be configured into 2⁴ = 16 distinct capability profiles by toggling each module on or off independently
.
The researchers tested GRAM across several settings and model sizes :
The GRAM research arrives alongside a high-stakes real-world example of the problem it aims to solve. In June 2025, the Trump administration imposed export controls on Anthropic's Claude Fable 5 and Mythos 5 models after cybersecurity concerns, blocking access for any foreign national—inside or outside the U.S., including foreign-national Anthropic employees . The ban lasted 18 days before the Commerce Department lifted it after a national security review
.
This episode illustrates the current state of AI access control: an entire model—with all its capabilities—gets treated as a single indivisible unit. If a model has a dangerous capability, the only option today is to withhold the entire system. GRAM proposes a finer-grained alternative: instead of locking down an entire model, a system could allow or disable specific categories of knowledge depending on the deployment context .
Anthropic's researchers explicitly identify GRAM as preliminary work and highlight several limitations :
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GRAM (Gradient Routed Auxiliary Modules) is an experimental pretraining method from Anthropic and AE Studio that routes dual use knowledge—like virology or cybersecurity—into dedicated modules inside an LLM, so those...
GRAM (Gradient Routed Auxiliary Modules) is an experimental pretraining method from Anthropic and AE Studio that routes dual use knowledge—like virology or cybersecurity—into dedicated modules inside an LLM, so those... In a setup with four dual use categories, a single GRAM trained model can theoretically be configured into 16 different capability profiles by turning specific modules on or off.
The technique arrives alongside real world policy debates: in June 2025 the Trump administration imposed—and later lifted—export controls on Anthropic's Claude Fable 5 and Mythos 5 models after cybersecurity concerns,...